Serial increase of IL-12 response and human leukocyte antigen-DR expression in severe sepsis survivors

@inproceedings{Wu2011SerialIO,
  title={Serial increase of IL-12 response and human leukocyte antigen-DR expression in severe sepsis survivors},
  author={Huang-Pin Wu and Chi-Chung Shih and Chun-Yao Lin and Chung-Ching Hua and Duen-yau Chuang},
  booktitle={Critical care},
  year={2011}
}
INTRODUCTION Sepsis-induced immunosuppression may result in death. The mechanisms of immune suppression include loss of macrophage and monocyte expression of the major histocompatibility complex, increased anti-inflammatory cytokine expression and decreased expression of proinflammatory cytokines. In this study, we sought to determine the mechanisms of immune suppression in severe sepsis by repeated detection. METHODS We designed this prospective observational study to measure monocyte human… CONTINUE READING