Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE mice.

@article{BenHur2007SerialIV,
  title={Serial in vivo MR tracking of magnetically labeled neural spheres transplanted in chronic EAE mice.},
  author={Tamir Ben-Hur and Ruud B van Heeswijk and Ofira Einstein and Michal Aharonowiz and Rong Xue and Emma E. Frost and Susumu Mori and Benjamin E. Reubinoff and Jeff W M Bulte},
  journal={Magnetic resonance in medicine},
  year={2007},
  volume={57 1},
  pages={164-71}
}
Neural stem cell (NSC) transplantation has been shown to attenuate the severity of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). Central to the future success of NSC transplantation in MS is the ability of transplanted cells to migrate from the site of transplantation to relevant foci of disease. Using magnetically labeled mouse neurospheres and human embryonic stem cell (hESC)-derived neurospheres, we applied serial magnetic resonance imaging (MRI… CONTINUE READING