Serial extracellular matrix changes in neointimal lesions of human coronary artery after percutaneous transluminal coronary angioplasty: clinical significance of early tenascin-C expression

@article{ImanakaYoshida2001SerialEM,
  title={Serial extracellular matrix changes in neointimal lesions of human coronary artery after percutaneous transluminal coronary angioplasty: clinical significance of early tenascin-C expression},
  author={Kyoko Imanaka-Yoshida and Ritsuko Matsuura and Naoki Isaka and Takeshi Nakano and Teruyo Sakakura and Toshimichi Yoshida},
  journal={Virchows Archiv},
  year={2001},
  volume={439},
  pages={185-190}
}
It has become clear that deposition of extracellular matrix(ECM) proteins is a major cause of human restenosis after percutaneous coronary angioplasty(PTCA). To define the composition and organization of the involved ECM in human restenotic tissue, we morphologically and semiquantitatively analyzed specimens obtained by means of directional coronary atherectomy at various stages after PTCA with anti-fibronectin, tenascin-C, collagens I and III, and PG-M/versican antibodies. Tenascin-C… CONTINUE READING