Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study.

@article{LpezAlarcn2015SerialDO,
  title={Serial determinations of asymmetric dimethylarginine and homocysteine during pregnancy to predict pre-eclampsia: a longitudinal study.},
  author={Mardia G L{\'o}pez-Alarc{\'o}n and Irene Montalvo-Velarde and V{\'i}ctor Sa{\'u}l Vital-Reyes and Juan Carlos Hinojosa-Cruz and Alfredo Lea{\~n}os-Miranda and Azucena Mart{\'i}nez-Basila},
  journal={BJOG : an international journal of obstetrics and gynaecology},
  year={2015},
  volume={122 12},
  pages={1586-92}
}
OBJECTIVE To evaluate the usefulness of serial determinations of asymmetric dimethylarginine (ADMA) and homocysteine (Hcy) concentrations during pregnancy to predict pre-eclampsia, taking into account maternal obesity and B vitamin status. DESIGN Longitudinal study. SETTING Two obstetric referral hospitals. SAMPLE Two hundred and fifty-two of 411 women invited to participate in the study. METHODS The women made monthly visits from ≤20 weeks of gestation until delivery for measurements… CONTINUE READING
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