Serial decline of kidney function as a novel biomarker for the progression of atherothrombotic disease.

@article{Rein2010SerialDO,
  title={Serial decline of kidney function as a novel biomarker for the progression of atherothrombotic disease.},
  author={Philipp Rein and Christoph Hubert Saely and Axel Muendlein and Alexander Vonbank and H einz Drexel},
  journal={Atherosclerosis},
  year={2010},
  volume={211 1},
  pages={348-52}
}
OBJECTIVE Impaired kidney function is associated with cardiovascular disease. However, from the available data it cannot be discerned which of the two entities presents first and entails the other. If renal dysfunction is first, a dynamic decline in the estimated glomerular filtration rate (eGFR) should predict vascular events and prove a useful biomarker for atherothrombotic disease. We therefore tested the hypothesis that a decrease in kidney function predicts future vascular events in a high… CONTINUE READING

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