Serial analysis of gene expression in adrenocortical hyperplasia caused by a germline PRKAR1A mutation.


CONTEXT Adrenocortical tumors have been studied at the molecular genetic and cytogenetic levels, but the gene expression profiles of normal and tumor adrenal tissue have not been extensively investigated. OBJECTIVE The objective of this study was to obtain information about transcriptome differences in hyperplastic adrenal cells. DESIGN AND PATIENTS We… (More)


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