Serial Regulation of Transcriptional Regulators in the Yeast Cell Cycle

@article{Simon2001SerialRO,
  title={Serial Regulation of Transcriptional Regulators in the Yeast Cell Cycle},
  author={Itamar Simon and J D Barnett and Nancy M. Hannett and Christopher T. Harbison and Nicola J. Rinaldi and Thomas L. Volkert and John J. Wyrick and Julia Zeitlinger and David Kenneth Gifford and T. Jaakkola and Richard A. Young},
  journal={Cell},
  year={2001},
  volume={106},
  pages={697-708}
}
Genome-wide location analysis was used to determine how the yeast cell cycle gene expression program is regulated by each of the nine known cell cycle transcriptional activators. We found that cell cycle transcriptional activators that function during one stage of the cell cycle regulate transcriptional activators that function during the next stage. This serial regulation of transcriptional activators forms a connected regulatory network that is itself a cycle. Our results also reveal how the… Expand

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