Serglycin expression: An independent marker of distant metastases in nasopharyngeal carcinoma.

@article{Chia2016SerglycinEA,
  title={Serglycin expression: An independent marker of distant metastases in nasopharyngeal carcinoma.},
  author={Claramae Shulyn Chia and Whee Sze Ong and Xin Jian Li and Yoke-Lim Soong and Fui Teen Chong and Hiang-Khoon Tan and K C Soo and C N Qian and B. T. Teh and N Gopalakrishna Iyer},
  journal={Head & neck},
  year={2016},
  volume={38 1},
  pages={21-8}
}
BACKGROUND Nasopharyngeal carcinoma (NPC) has a high propensity for metastasis. The purpose of this study was for us to determine whether serglycin expression can be used to predict distant metastases. METHODS Serglycin expression of tumor tissue of 112 patients with NPC was assessed based on percentage of tumor cells expressing serglycin, staining intensity, percentage of tumor-infiltrated lymphocyte (TIL) expressing serglycin and TIL-staining intensity. RESULTS Risk factors for distant… CONTINUE READING

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