Sera of glaucoma patients show autoantibodies against myelin basic protein and complex autoantibody profiles against human optic nerve antigens

@article{Joachim2007SeraOG,
  title={Sera of glaucoma patients show autoantibodies against myelin basic protein and complex autoantibody profiles against human optic nerve antigens},
  author={Stephanie C Joachim and Jan Reichelt and Simone Berneiser and Norbert Pfeiffer and Franz Herman Grus},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2007},
  volume={246},
  pages={573-580}
}
BackgroundThe aim of this study was to gain more information about the possible immunological mechanisms in glaucoma. We analyzed the complex autoantibody patterns against human optic nerve antigens in sera of patients with glaucoma and tried to identify important antigens.MethodsSera of 133 patients were included: healthy control subjects (n = 44), primary open-angle glaucoma (n = 44), and normal tension glaucoma patients (n = 45). The sera were tested against Western blots of human optic… CONTINUE READING
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