Sera from habitual aborters induce monocyte procoagulant activity: a lymphocyte-dependent event.

@article{Laskin1994SeraFH,
  title={Sera from habitual aborters induce monocyte procoagulant activity: a lymphocyte-dependent event.},
  author={Carl A Laskin and A Chuma and Lilyana Angelov and Garry Neil and Gary A. Levy and Nancy C. Shaw George Mason and C A Solon{\'i}nka and Edward I. Cole},
  journal={Clinical immunology and immunopathology},
  year={1994},
  volume={73 2},
  pages={235-44}
}
Placental thrombosis is a prominent feature in patients with unexplained recurrent fetal loss. To determine whether induction of monocyte procoagulant activity might be a relevant mechanism for unexplained recurrent fetal loss, peripheral blood mononuclear cells isolated from normal healthy controls were cocultured with (a) sera from normal healthy controls (n = 16), (b) sera from habitual aborters (n = 41), and (c) lipopolysaccharide as a positive control. Sera from three patients were… CONTINUE READING