Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms.

@article{Yang2005Ser1928IA,
  title={Ser1928 is a common site for Cav1.2 phosphorylation by protein kinase C isoforms.},
  author={Lin Yang and Guoxia Liu and Sergey I. Zakharov and John P. Morrow and Vitali O Rybin and Susan F. Steinberg and Steven O. Marx},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 1},
  pages={207-14}
}
Voltage-dependent Ca(2+) channel (Ca(v)1.2, L-type Ca(2+) channel) function is highly regulated by hormones and neurotransmitters in large part through the activation of kinases and phosphatases. Regulation of Ca(v)1.2 by protein kinase C (PKC) is of significant physiologic importance, mediating, in part, the cardiac response to hormonal regulation. Although PKC has been reported to mediate activation and/or inhibition of Ca(v)1.2 function, the molecular mechanisms mediating the response have… CONTINUE READING