Sequential stages of human T lymphocyte differentiation ( prothymocyte / T cell markers / T cell functions / thymic factors )

  • JEAN-LOUIS TOURAINE, JOHN W. HADDENt

Abstract

Induction of thymus-dependent lymphocyte (T cell) differentiation was performed in vitro with thymic factors as inducers. T cell precursors from human bone marrow first expressed surface differentiation antigens and then acquired the capacity to form rosettes with sheep erythrocytes. The latter marker could not be induced when cells with differentiation… (More)

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