Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: evidence for a proteoglycan-independent virus entry pathway.

@article{Banfield1995SequentialIO,
  title={Sequential isolation of proteoglycan synthesis mutants by using herpes simplex virus as a selective agent: evidence for a proteoglycan-independent virus entry pathway.},
  author={Bruce W. Banfield and Yves Leduc and Lesley Esford and Karin C. Schubert and Frank Tufaro},
  journal={Journal of virology},
  year={1995},
  volume={69 6},
  pages={3290-8}
}
A novel mouse L-cell mutant cell line defective in the biosynthesis of glycosaminoglycans was isolated by selection for cells resistant to herpes simplex virus (HSV) infection. These cells, termed sog9, were derived from mutant parental gro2C cells, which are themselves defective in heparan sulfate biosynthesis and 90% resistant to HSV type 1 (HSV-1… CONTINUE READING