Sequential endocrine therapy and chemotherapy in metastatic breast cancer: Effects on survival

@article{Manni1981SequentialET,
  title={Sequential endocrine therapy and chemotherapy in metastatic breast cancer: Effects on survival},
  author={Andrea Manni and Olof H. Pearson and James S. Marshall and Bahauddin M. Arafah},
  journal={Breast Cancer Research and Treatment},
  year={1981},
  volume={1},
  pages={97-103}
}
Follow-up data of 113 patients with stage IV breast cancer treated with the antiestrogen tamoxifen show that the duration of remission is in average in excess of 21 months with a median of 16 months. Survival from start of antiestrogen therapy was significantly longer in patients who responded to tamoxifen, in those with dominant site of disease in the soft tissue, and in those with less extensive metastatic involvement. Overall survival from onset of metastasis was also much longer in patients… CONTINUE READING

References

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Medical hypophysectomy in advanced breast cancer

A Manni, BM Arafah, OH Pearson
In DP Rose (ed): Endocrinology of Cancer, • 1981

: 45 - month follow - up of a prospective , randomized clinical trial

A Manni, J Trujillo, J Marshall, OH Pearson
1980

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