Sequential changes in the signal transduction responses of skeletal muscle following food deprivation.

@article{Lange2006SequentialCI,
  title={Sequential changes in the signal transduction responses of skeletal muscle following food deprivation.},
  author={Pieter de Lange and Paola Farina and Maria Moreno and Maurizio Ragni and Assunta Lombardi and Elena Silvestri and Lavinia Burrone and Antonia Lanni and Fernando Goglia},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2006},
  volume={20 14},
  pages={2579-81}
}
Coping with reduced energy sources entails drastic morphological and functional changes in skeletal muscle, but the sequence of events required classification. We found that gastrocnemius muscle from food-deprived rats shows acute rises in peroxisome proliferator activated receptor (PPAR) gamma coactivator (PGC) -1alpha/PPAR delta nuclear protein and myosin heavy chain (MHC) Ib protein, while type I fibers accumulate and the muscle tissue appears redder. AMP levels, phosphorylation of both AMP… CONTINUE READING

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