Sequential bilateral striatal lesions have additive effects on single skilled limb use in rats

@article{Faraji2007SequentialBS,
  title={Sequential bilateral striatal lesions have additive effects on single skilled limb use in rats},
  author={Jamshid Faraji and Gerlinde A S Metz},
  journal={Behavioural Brain Research},
  year={2007},
  volume={177},
  pages={195-204}
}
Unilateral dopamine depletion in rats induced by injection of 6-hydroxydopamine (6-OHDA) into the nigrostriatal system causes permanent impairments in limb use. The disturbances in limb use, including impairments in skilled reaching, are most severe on the side contralateral to the lesion. A number of studies, however, have also described ipsilateral deficits in skilled reaching. The purpose of this study was to investigate the effects of sequential bilateral striatal 6-OHDA lesions on skilled… CONTINUE READING
BETA

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Similar Papers

Loading similar papers…