Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: evidence for a conserved myoblast differentiation program in skeletal muscle.

@article{Lin1994SequentialAO,
  title={Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: evidence for a conserved myoblast differentiation program in skeletal muscle.},
  author={Z X Lin and M. H. Lu and Timothy Schultheiss and Jayoung Choi and Sybil Holtzer and C Dilullo and Donald A. Fischman and Howard Holtzer},
  journal={Cell motility and the cytoskeleton},
  year={1994},
  volume={29 1},
  pages={1-19}
}
Based on the assumption that a conserved differentiation program governs the assembly of sarcomeres in skeletal muscle in a manner analogous to programs for viral capsid assembly, we have defined the temporal and spatial distribution of 10 muscle-specific proteins in mononucleated myoblasts as a function of the time after terminal cell division. Single cells in mitosis were identified in monolayer cultures of embryonic chicken pectoralis, followed for selected time points (0-24 h postmitosis… CONTINUE READING

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