Sequential activation of different Ca2+ entry pathways upon cholinergic stimulation in mouse pancreatic acinar cells.

@article{Camello1999SequentialAO,
  title={Sequential activation of different Ca2+ entry pathways upon cholinergic stimulation in mouse pancreatic acinar cells.},
  author={Cristina Camello and Jos{\'e} Antonio Pariente and Gin{\'e}s M Salido and Pedro Javier Camello},
  journal={The Journal of physiology},
  year={1999},
  volume={516 ( Pt 2)},
  pages={
          399-408
        }
}
  • Cristina Camello, José Antonio Pariente, +1 author Pedro Javier Camello
  • Published 1999
  • Chemistry, Medicine
  • The Journal of physiology
  • 1. We have studied capacitative calcium entry (CCE) under different experimental conditions in fura-2-loaded mouse pancreatic acinar cells by digital microscopic fluorimetry. CCE was investigated during [Ca2+]i decay after cell stimulation with a supramaximal concentration of ACh (10 microM) or during Ca2+ readmission in Ca2+-depleted cells (pretreated with thapsigargin or ACh). 2. La3+ and Zn2+ (100 microM) inhibited CCE during Ca2+ readmission but had negligible effects during ACh decay. In… CONTINUE READING

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