Sequential action of two-component genetic switches regulates the PHO regulon in Bacillus subtilis.

@article{Hulett1994SequentialAO,
  title={Sequential action of two-component genetic switches regulates the PHO regulon in Bacillus subtilis.},
  author={F. Marion Hulett and J J Lee and Liang Ru Shi and Guifeng Sun and Robert Chesnut and E. V. Sharkova and M F Duggan and Nadine Kapp},
  journal={Journal of bacteriology},
  year={1994},
  volume={176 5},
  pages={1348-58}
}
Bacillus subtilis has an alkaline phosphatase (APase) gene family composed of at least four genes. All members of this gene family are expressed postexponentially, either in response to phosphate starvation or sporulation induction or, in some cases, in response to both. The phoA gene (formerly called phoAIV) and the phoB gene (formerly called phoAIII) products have both been isolated from phosphate-starved cells, and a mutation in either gene decreased the total APase expressed under phosphate… CONTINUE READING