Sequential Loss of Two Neighboring Exons of the Tropoelastin Gene During Primate Evolution

  title={Sequential Loss of Two Neighboring Exons of the Tropoelastin Gene During Primate Evolution},
  author={Zolt{\'a}n Szab{\'o} and Simona A. Levi-Minzi and Angela M. Christiano and Carole Struminger and M. Stoneking and Mark A. Batzer and Charles D. Boyd},
  journal={Journal of Molecular Evolution},
Previous evidence has demonstrated the absence of exons 34 and 35 within the 3′ end of the human tropoelastin (ELN) gene. These exons encode conserved polypeptide domains within tropoelastin and are found in the ELN gene in vertebrate species ranging from chickens to rats to cows. We have analyzed the ELN gene in a variety of primate species to determine whether the absence of exons 34 and 35 in humans either is due to allelic variation within the human population or is a general characteristic… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 26 extracted citations

Meat-adaptive genes and the evolution of slower aging in humans.

The Quarterly review of biology • 2004
View 20 Excerpts
Highly Influenced

Elastin-driven genetic diseases.

Matrix biology : journal of the International Society for Matrix Biology • 2018
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 16 references

Molecular cloning

J Sambrook, EF Fritsch, T Maniatis
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, • 1989
View 3 Excerpts
Highly Influenced

The encyclopedia of mammals

DW Macdonald
Facts on File, • 1993
View 1 Excerpt

Properties and function of lysyl oxidase.

American journal of respiratory cell and molecular biology • 1991
View 2 Excerpts

Similar Papers

Loading similar papers…