Sequential Activation of the 5-HT1A Serotonin Receptor and TrkB Induces the Serotonergic Neuronal Phenotype

@article{Galter2000SequentialAO,
  title={Sequential Activation of the 5-HT1A Serotonin Receptor and TrkB Induces the Serotonergic Neuronal Phenotype},
  author={D. Galter and K. Unsicker},
  journal={Molecular and Cellular Neuroscience},
  year={2000},
  volume={15},
  pages={446-455}
}
Serotonin (5-HT) is an important factor controlling survival, differentiation, and plasticity of neurons in serotonergic target regions of the brain and has been implicated in major psychiatric and autonomic disorders. Relatively little is known, however, of factors controlling differentiation and plasticity of developing and adult 5-HT neurons. We show now that 5-HT, the 5-HT1(A) receptor, brain-derived neurotrophic factor (BDNF), and its receptor, trkB, form an auto/paracrine loop for the… Expand
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4
5
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References

SHOWING 1-10 OF 56 REFERENCES
5-HT1a receptors mediate the neurotrophic effect of serotonin on developing dentate granule cells.
Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
Effects of neonatal serotonin depletion on the development of rat dentate granule cells.
Comparative localization of serotonin1A, 1C, and 2 receptor subtype mRNAs in rat brain
...
1
2
3
4
5
...