Sequencing of megabase plus DNA by hybridization: theory of the method.

Abstract

A mismatch-free hybridization of oligonucleotides containing from 11 to 20 monomers to unknown DNA represents, in essence, a sequencing of a complementary target. Realizing this, we have used probability calculations and, in part, computer simulations to estimate the types and numbers of oligonucleotides that would have to be synthesized in order to… (More)

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Cite this paper

@article{Drmanac1989SequencingOM, title={Sequencing of megabase plus DNA by hybridization: theory of the method.}, author={Radoje Drmanac and Ivan Labat and I Brukner and Radomir Crkvenjakov}, journal={Genomics}, year={1989}, volume={4 2}, pages={114-28} }