Sequencing of a tick-borne encephalitis virus from Ixodes ricinus reveals a thermosensitive RNA switch significant for virus propagation in ectothermic arthropods.

@article{Elvng2011SequencingOA,
  title={Sequencing of a tick-borne encephalitis virus from Ixodes ricinus reveals a thermosensitive RNA switch significant for virus propagation in ectothermic arthropods.},
  author={Annelie Elv{\"a}ng and Wessam Melik and Yann Bertrand and Mikael L{\"o}nn and Magnus Johansson},
  journal={Vector borne and zoonotic diseases},
  year={2011},
  volume={11 6},
  pages={649-58}
}
Tick-borne encephalitis virus (TBEV) is a flavivirus with major impact on global health. The geographical TBEV distribution is expanding, thus making it pivotal to further characterize the natural virus populations. In this study, we completed the earlier partial sequencing of a TBEV pulled out of a pool of RNA extracted from 115 ticks collected on Torö in the Stockholm archipelago. The total RNA was sufficient for all sequencing of a TBEV genome (Torö-2003), without conventional enrichment… CONTINUE READING
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