Sequencing and expression of complementary DNA for the general transcription factor BTF3

@article{Zheng1990SequencingAE,
  title={Sequencing and expression of complementary DNA for the general transcription factor BTF3},
  author={Xin Min Zheng and D. Black and Pierre Chambon and Jean Marc Egly},
  journal={Nature},
  year={1990},
  volume={344},
  pages={556-559}
}
THE initiation of transcription of eukaryotic genes involves the ordered assembly of a multiprotein complex on proximal promoter elements such as the TATA box1,2. In addition to RNA polymerase II (otherwise RNA pol II, RNA polymerase B), four general transcription factors are required for initiation of transcription3–6: BTF1 (also referred to as TFIID) which has recently been cloned from yeast7–11, BTF2, BTF3 and STF. The first step in assembly of the initiation complex is the stable binding of… CONTINUE READING