Sequencing Illustrates the Transcriptional Response of Legionella pneumophila during Infection and Identifies Seventy Novel Small Non-Coding RNAs

@inproceedings{Weissenmayer2011SequencingIT,
  title={Sequencing Illustrates the Transcriptional Response of Legionella pneumophila during Infection and Identifies Seventy Novel Small Non-Coding RNAs},
  author={Barbara A. Weissenmayer and James G. D. Prendergast and Amanda J. Lohan and Brendan J. Loftus},
  booktitle={PloS one},
  year={2011}
}
Second generation sequencing has prompted a number of groups to re-interrogate the transcriptomes of several bacterial and archaeal species. One of the central findings has been the identification of complex networks of small non-coding RNAs that play central roles in transcriptional regulation in all growth conditions and for the pathogen's interaction with and survival within host cells. Legionella pneumophila is a gram-negative facultative intracellular human pathogen with a distinct… CONTINUE READING

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