Sequences within Both the 5′ UTR and Gag Are Required for Optimal In Vivo Packaging and Propagation of Mouse Mammary Tumor Virus (MMTV) Genomic RNA

@inproceedings{Mustafa2012SequencesWB,
  title={Sequences within Both the 5′ UTR and Gag Are Required for Optimal In Vivo Packaging and Propagation of Mouse Mammary Tumor Virus (MMTV) Genomic RNA},
  author={Farah Mustafa and Dhuha Al Amri and Farah Al Ali and Noor Al Sari and Sarah Al Suwaidi and Preethi Jayanth and Pretty S. Philips and Tahir A. Rizvi},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND This study mapped regions of genomic RNA (gRNA) important for packaging and propagation of mouse mammary tumor virus (MMTV). MMTV is a type B betaretrovirus which preassembles intracellularly, a phenomenon distinct from retroviruses that assemble the progeny virion at cell surface just before budding such as the type C human and feline immunodeficiency viruses (HIV and FIV). Studies of FIV and Mason-Pfizer monkey virus (MPMV), a type D betaretrovirus with similar intracellular virion… CONTINUE READING