Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes.

@article{Pealva1990SequencesOI,
  title={Sequences of isopenicillin N synthetase genes suggest horizontal gene transfer from prokaryotes to eukaryotes.},
  author={Miguel A Pe{\~n}alva and Andr{\'e}s Moya and Joaqu{\'i}n Dopazo and Daniel Ram{\'o}n},
  journal={Proceedings. Biological sciences},
  year={1990},
  volume={241 1302},
  pages={164-9}
}
Evolutionary distances between bacterial and fungal isopenicillin N synthetase (IPNS) genes have been compared to distances between the corresponding 5S rRNA genes. The presence of sequences homologous to the IPNS gene has been examined in DNAs from representative prokaryotic organisms and Ascomycotina. The results of both analyses strongly support two different events of horizontal transfer of the IPNS gene from bacteria to filamentous fungi. This is the first example of such a type of… CONTINUE READING

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