Sequences of antigenic epitopes of streptokinase identified via random peptide libraries displayed on phage.

Abstract

Though streptokinase (SK) is widely used to treat humans with thrombotic disease, it is antigenic and anti-SK antibody causes allergic reactions and neutralizes SK's therapeutic effects. To pinpoint the fine structure of two immunodominant, continuous epitopes in SK, we used unconstrained 15 and 6-mer random peptide libraries displayed on phage (theoretical… (More)

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Cite this paper

@article{ParhamiSeren1997SequencesOA, title={Sequences of antigenic epitopes of streptokinase identified via random peptide libraries displayed on phage.}, author={Behnaz Parhami-Seren and Trevor Keel and Guy L Reed}, journal={Journal of molecular biology}, year={1997}, volume={271 3}, pages={333-41} }