Sequences intervening between the core packaging determinants are dispensable for maintaining the packaging potential and propagation of feline immunodeficiency virus transfer vector RNAs.

@article{Mustafa2005SequencesIB,
  title={Sequences intervening between the core packaging determinants are dispensable for maintaining the packaging potential and propagation of feline immunodeficiency virus transfer vector RNAs.},
  author={Farah Mustafa and Akela A. Ghazawi and Preethi Jayanth and Pretty Susan Phillip and Jahabar Ali and Tahir A. Rizvi},
  journal={Journal of virology},
  year={2005},
  volume={79 21},
  pages={
          13817-21
        }
}
The packaging determinants of feline immunodeficiency virus (FIV) consist of two discontinuous core regions, extending from R to approximately 150 bp of the 5' untranslated region and the first approximately 100 bp of gag. However, the role of sequences intervening between the core regions in packaging has not been clear. A mutational analysis was conducted to determine whether the intervening sequences played a role in FIV RNA packaging, using an in vivo packaging assay complemented with… CONTINUE READING

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