Sequence variation of MicroRNAs and their binding sites in Arabidopsis.

  title={Sequence variation of MicroRNAs and their binding sites in Arabidopsis.},
  author={Ian M. Ehrenreich and Michael D. Purugganan},
  journal={Plant physiology},
  volume={146 4},
Major differences exist between plants and animals both in the extent of microRNA (miRNA)-based gene regulation and the sequence complementarity requirements for miRNA-messenger RNA pairing. Whether these differences affect how these sites evolve at the molecular level is unknown. To determine the extent of sequence variation at miRNAs and their targets in a plant species, we resequenced 16 miRNA families (66 miRNAs in total) and all 52 of the characterized binding sites for these miRNAs in the… CONTINUE READING
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