Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men.

Abstract

BACKGROUND Previous studies have found associations between mitochondrial DNA (mtDNA) mutations and several cancer types. Recently, we found that mutations in the mtDNA gene cytochrome c oxidase subunit 1 (COI) were both linked to and associated with prostate cancer (PCa) in Caucasian men. Here we examine the association between COI mutations and PCa in… (More)
DOI: 10.1002/pros.20943

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