Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body weight in native cattle breeds in China.

@article{Huang2011SequenceVI,
  title={Sequence variants in the bovine nucleophosmin 1 gene, their linkage and their associations with body weight in native cattle breeds in China.},
  author={Yongzhen Huang and Hua He and Junhui Wang and Zhuan-jian Li and Xian-yong Lan and Chuzhao Lei and E. P. Zhang and Chun Lei Zhang and Qingwu W. Shen and Hui-Ming Chen},
  journal={Animal genetics},
  year={2011},
  volume={42 5},
  pages={556-9}
}
The nucleophosmin (nucleolar phosphoprotein B23, numatrin) gene (NPM1, previously known as nucleophosmin/nucleoplasmin family, member 1) encodes a multifunctional nucleolar phosphoprotein that plays a crucial role in cell growth and homeostasis. Seven sequence variants (SVs) were identified in the coding region of bovine NPM1, five of which were in complete linkage disequilibrium. Eight different haplotypes were identified, of which two major haplotypes have a frequency of 23.2% and 20.4… CONTINUE READING

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