Sequence-specific size, structure, and stability of tight protein knots.

@article{Dzubiella2009SequencespecificSS,
  title={Sequence-specific size, structure, and stability of tight protein knots.},
  author={Joachim Dzubiella},
  journal={Biophysical journal},
  year={2009},
  volume={96 3},
  pages={
          831-9
        }
}
Approximately 1% of known protein structures display knotted configurations in their native fold, but the function of these configurations is not understood. It has been speculated that the entanglement may inhibit mechanical protein unfolding or transport, e.g., as in cellular threading or translocation processes through narrow biological pores. Protein knot manipulation, e.g., knot tightening and localization, has become possible in single-molecule experiments. Here, we investigate tight… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 21 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Tightening the phytochrome knot by single molecule atomic force microscopy

  • T. Bornschlögl, D. Anstrom, J. Dzubiella, M. Rief, K. T. Forest
  • 2008
Highly Influential
8 Excerpts

Similar Papers

Loading similar papers…