Sequence-specific interactions between promoter DNA and the RNA polymerase sigma factor E.

@article{Tatti1995SequencespecificIB,
  title={Sequence-specific interactions between promoter DNA and the RNA polymerase sigma factor E.},
  author={Kathleen M. Tatti and Marsha Shuler and Charles P Moran},
  journal={Journal of molecular biology},
  year={1995},
  volume={253 1},
  pages={
          8-16
        }
}
In order to determine which amino acyl residues in a secondary sigma factor govern its specificity of recognition at the -35 region of promoters, we examined the effects of amino acid substitutions in sigma E in Bacillus subtilis that made the sequence of its putative -35 recognition region more similar to another sigma factor in B. subtilis, sigma K. We found that a single amino acid substitution at position 217 of sigma E resulted in a sigma factor that could direct transcription from sigma K… CONTINUE READING

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