Sequence requirements for the termination of rolling-circle replication of plasmid pT181.

@article{Zhao1997SequenceRF,
  title={Sequence requirements for the termination of rolling-circle replication of plasmid pT181.},
  author={Anmin Zhao and Saleem Ayaz Khan},
  journal={Molecular microbiology},
  year={1997},
  volume={24 3},
  pages={535-44}
}
Most small multicopy plasmids of Gram-positive bacteria and many in Gram-negative bacteria replicate by a rolling-circle (RC) mechanism. The replication initiator proteins encoded by the RC plasmids and single-stranded bacteriophages of Escherichia coli have origin-specific nicking-closing activities that are required for the initiation and termination of RC replication. We have investigated the sequence requirements for termination of RC replication of plasmid pT181. The initiator nick site is… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Similar Papers

Loading similar papers…