Sequence requirements for activation of the HIV-1 LTR by human cytomegalovirus.

@article{Biegalke1991SequenceRF,
  title={Sequence requirements for activation of the HIV-1 LTR by human cytomegalovirus.},
  author={Bonita J. Biegalke and Adam P. Geballe},
  journal={Virology},
  year={1991},
  volume={183 1},
  pages={
          381-5
        }
}
Human cytomegalovirus (CMV) alters the growth and expression of human immunodeficiency virus-1 (HIV-1) in cell culture and may accelerate the course of AIDS in HIV-1 infected patients. CMV infection or the expression of the CMV immediate early genes has been shown to activate gene expression directed by the HIV-1 LTR. However, the cis-acting elements within the HIV-1 LTR that confer responsiveness to CMV have not been clearly delineated. We report on investigations in human fibroblasts designed… CONTINUE READING
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