Sequence polymorphism of BoLA-DQA

  title={Sequence polymorphism of BoLA-DQA},
  author={Annette Gelhaus and Christina Wippern and Dieter Mehlitz and R Horstmann},
The DR and DQ genes of the major histocompatibility complex of cattle (BoLA) resemble those of other mammalian species except for a certain variability in the number of DQA and DQB loci, which appears to be a feature unique to ruminants. Cattle possess two distinct types of DQA loci. They are represented by genomic clones termed IV] and AS, which differ by approximately 25% in the sequences of their second exons (Van der Poel et al. 1990; Sigurdarddttir et al. 1991 a). Exon 2 probes of W1 and… CONTINUE READING
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