Sequence of the human insulin gene

@article{Bell1980SequenceOT,
  title={Sequence of the human insulin gene},
  author={G. Bell and R. Pictet and W. Rutter and B. Cordell and E. Tischer and H. Goodman},
  journal={Nature},
  year={1980},
  volume={284},
  pages={26-32}
}
  • G. Bell, R. Pictet, +3 authors H. Goodman
  • Published 1980
  • Biology, Medicine
  • Nature
  • The human insulin gene contains two intervening sequences, one is within the region transcribed into the 5′-untranslated segment of the mRNA and the other interrupts the C-peptide encoding region. A comparison of the human with the rat insulin genes indicates potential regulatory regions in the DNA segment preceding the gene and suggests that the ancestral form of the insulin gene had two intervening sequences. 
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    References

    SHOWING 1-10 OF 36 REFERENCES
    Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.
    • 789
    • PDF