Sequence of centromere separation: differential replication of pericentric heterochromatin in multicentric chromosomes

Abstract

The dicentric and multicentric chromosomes in L cells and a brain tumor cell line of mouse display only one site of kinetochore formation associated with the ‘active’ centromere. The accessory or ‘inactive’ centromeres show premature separation. These cell lines were treated with 10−6 M 5-bromodeoxyuridine (BrdUrd) followed by anti-BrdUrd antibody to study… (More)
DOI: 10.1007/BF00286919

Topics

1 Figure or Table

Slides referencing similar topics