Sequence motifs for calmodulin recognition.

  title={Sequence motifs for calmodulin recognition.},
  author={Allen R. Rhoads and Felix Friedberg},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  volume={11 5},
Calmodulin (CaM) is recognized as a major calcium sensor and orchestrator of regulatory events through its interaction with a diverse group of cellular proteins. Many investigations have focused on defining the region of interaction between CaM and its cellular targets and the action of CaM on target protein function. Because CaM can bind with high affinity to a relatively small alpha-helical region of many proteins, success in clearly defining the essential elements of CaM binding motifs seems… CONTINUE READING
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