Sequence errors described in GenBank: a means to determine the accuracy of DNA sequence interpretation.

@article{Krawetz1989SequenceED,
  title={Sequence errors described in GenBank: a means to determine the accuracy of DNA sequence interpretation.},
  author={Stephen A. Krawetz},
  journal={Nucleic acids research},
  year={1989},
  volume={17 10},
  pages={3951-7}
}
The accuracy of nucleic acid sequence data interpretation was determined by assessing and quantifying the discrepancies reported in the GenBank database. This permitted the calculation of an Error Rate (ER) for nucleic acid sequence determination. If one assumes that most entries (TB, Total Bases) were independently verified or those without reported discrepancies were correct, the ER is 0.368 errors per 1000 bases. However, if one assumes that only those sequences with reported discrepancies… CONTINUE READING
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Hindley, laboratory techniques in biochemistry and molecular biology DNA sequencing

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