Sequence effects in single-base loops for quadruplexes.

  title={Sequence effects in single-base loops for quadruplexes.},
  author={Aurore Gu{\'e}din and Anne De Cian and Julien Gros and L. Lacroix and Jean-Louis Mergny},
  volume={90 5},
Intramolecular G-quadruplexes formed by a single DNA strand have attracted much interest due to the possibility that they may form in telomeres, oncogene promoter sequences and other biologically relevant regions of the genome. Therefore, it is important to understand the rules that govern the formation of these intramolecular structures and to determine their stabilities. We compared here 27 different sequences containing four tracts of three guanines with a medium (3) or relatively long (6-9… CONTINUE READING


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