Sequence diversity of Neisseria meningitidis 16S rRNA genes and use of 16S rRNA gene sequencing as a molecular subtyping tool.

@article{Sacchi2002SequenceDO,
  title={Sequence diversity of Neisseria meningitidis 16S rRNA genes and use of 16S rRNA gene sequencing as a molecular subtyping tool.},
  author={Cl{\'a}udio Tavares Sacchi and Anne M. Whitney and Michael W. Reeves and Leonard W. Mayer and Tanja Popovi{\'c}},
  journal={Journal of clinical microbiology},
  year={2002},
  volume={40 12},
  pages={
          4520-7
        }
}
We investigated the diversity of the primary sequences of 16S rRNA genes among Neisseria meningitidis strains (Men) and evaluated the use of this approach as a molecular subtyping tool. We aligned and compared a 1,417-bp fragment of the 16S rRNA gene from 264 Men strains of serogroups A, B, C, and Y (MenA, MenB, MenC, and MenY, respectively) isolated throughout the world over a 30-year period. Thirty-one positions of difference were found among 49 16S types: differences between types ranged… CONTINUE READING
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