Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi.

@article{Roberts1993SequenceDA,
  title={Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi.},
  author={Sigrid C. Roberts and K G Swihart and M W Agey and Ramesh Ramamoorthy and Mary E Wilson and J. E. Donelson},
  journal={Molecular and biochemical parasitology},
  year={1993},
  volume={62 2},
  pages={157-71}
}
During in vitro growth Leishmania chagasi promastigotes differentially express 3 classes of RNAs encoding the major surface protease (MSP) gp63 that can be distinguished by their unique 3' untranslated regions. Here we show that the three classes (logarithmic-specific, stationary-specific and constitutively expressed) are encoded by a family of at least 4 tandem stationary genes (mspS2, mspS1, mspS3 and mspS5) followed by twelve or more logarithmic genes (mspL genes), one constitutive gene… CONTINUE READING