Sequence diversity and evolution of antimicrobial peptides in invertebrates.

  title={Sequence diversity and evolution of antimicrobial peptides in invertebrates.},
  author={Anchalee Tassanakajon and Kunlaya Somboonwiwat and Piti Amparyup},
  journal={Developmental and comparative immunology},
  volume={48 2},
Antimicrobial peptides (AMPs) are evolutionarily ancient molecules that act as the key components in the invertebrate innate immunity against invading pathogens. Several AMPs have been identified and characterized in invertebrates, and found to display considerable diversity in their amino acid sequence, structure and biological activity. AMP genes appear to have rapidly evolved, which might have arisen from the co-evolutionary arms race between host and pathogens, and enabled organisms to… CONTINUE READING
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