Sequence conservation in field and experimental isolates of Borna disease virus.

@article{Schneider1994SequenceCI,
  title={Sequence conservation in field and experimental isolates of Borna disease virus.},
  author={Patricia A Schneider and Thomas Briese and Wolfgang Zimmermann and Holger Ludwig and W. Ian Lipkin},
  journal={Journal of virology},
  year={1994},
  volume={68 1},
  pages={63-8}
}
Coding and noncoding sequences were analyzed from field and experimental isolates of Borna disease virus. For a 24-kDa protein, maximum divergence was 1.5% at the predicted amino acid level and 3.1% at the nucleotide level. For a 40-kDa protein, maximum divergence was 1.1% at the predicted amino acid level and 4.1% at the nucleotide level. The highest variability in sequence (10%) was found in a 40-nucleotide stretch of genomic RNA between coding sequences for the 40- and 24-kDa proteins. The… CONTINUE READING

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