Sequence capture of ultraconserved elements from bird museum specimens.

  title={Sequence capture of ultraconserved elements from bird museum specimens.},
  author={John E McCormack and Whitney L. E. Tsai and Brant C. Faircloth},
  journal={Molecular ecology resources},
  volume={16 5},
New DNA sequencing technologies are allowing researchers to explore the genomes of the millions of natural history specimens collected prior to the molecular era. Yet, we know little about how well specific next-generation sequencing (NGS) techniques work with the degraded DNA typically extracted from museum specimens. Here, we use one type of NGS approach, sequence capture of ultraconserved elements (UCEs), to collect data from bird museum specimens as old as 120 years. We targeted 5060 UCE… CONTINUE READING
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