Sequence-based identification of 3D structural modules in RNA with RMDetect

@article{Cruz2011SequencebasedIO,
  title={Sequence-based identification of 3D structural modules in RNA with RMDetect},
  author={Jos{\'e} Almeida Cruz and Eric Westhof},
  journal={Nature Methods},
  year={2011},
  volume={8},
  pages={513-519}
}
Structural RNA modules, sets of ordered non-Watson-Crick base pairs embedded between Watson-Crick pairs, have central roles as architectural organizers and sites of ligand binding in RNA molecules, and are recurrently observed in RNA families throughout the phylogeny. Here we describe a computational tool, RNA three-dimensional (3D) modules detection, or RMDetect, for identifying known 3D structural modules in single and multiple RNA sequences in the absence of any other information. Currently… CONTINUE READING