Sequence and structural analyses of NSP4 proteins from human group A rotavirus strains detected in Tunisia.

@article{Fredj2014SequenceAS,
  title={Sequence and structural analyses of NSP4 proteins from human group A rotavirus strains detected in Tunisia.},
  author={Mouna Ben Hadj Fredj and M{\'e}riam Ben Hamida-Reba{\"i} and Mark K Zeller and Elizabeth Heylen and Marc van Ranst and Jelle Matthijnssens and Abdelhalim Trabelsi},
  journal={Pathologie-biologie},
  year={2014},
  volume={62 3},
  pages={146-51}
}
BACKGROUND The NSP4 protein of group A rotavirus (RVA) has been recognized as a viral enterotoxin and plays important roles in viral pathogenesis and morphogenesis. Domains involved in structural and functional interactions have been proposed mainly based on the simian SA11 strain. METHODS NSP4 has been classified into 15 different genotypes (E1-E15), and the aim of this study was to analyze the sequences of 46 RVA strains in order to determine the aminoacid (aa) differences between E1 and E2… CONTINUE READING

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