Sequence and properties of the message encoding Tetrahymena hv1, a highly evolutionarily conserved histone H2A variant that is associated with active genes

@article{White1988SequenceAP,
  title={Sequence and properties of the message encoding Tetrahymena hv1, a highly evolutionarily conserved histone H2A variant that is associated with active genes},
  author={E. M. White and D. L. Shapiro and C David Allis and M. A. Gorovsky},
  journal={Nucleic acids research},
  year={1988},
  volume={16 1},
  pages={179-98}
}
hv1 is a histone H2A variant found in the transcriptionally active Tetrahymena macronucleus, but not in the transcriptionally inert micronucleus. hv1 also contains antigenic determinants conserved in the histone complements of representatives of all four eukaryotic kingdoms. A cDNA clone encoding hv1 has been isolated and sequenced. Comparison of the derived protein sequence of hv1 with that of the chicken variant H2A.F and the sea urchin variant H2A.F/Z reveals remarkable homology in all but… CONTINUE READING

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The Molecular Biology of Ciliated Protozoa

M. A. Gorovsky
1986
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